3 anatomical regions · baseline study
Pre-treatment staging — breast cancer
Female, 43 · initial workup · staging before treatment eligibility
Structured report
organ by organ · pathology highlighted- Scope
- CT of the chest, abdomen and pelvis before and after contrast administration
- Thyroid
- not enlarged, heterogeneous; possible features of autoimmune thyroiditis — detailed assessment on ultrasound
- Lungs
- normally aerated; fibrotic/post-inflammatory changes at both lung bases; several focal lesions in both lungs suspicious for metastases, the largest up to 13 mm in segment 3 of the right lung and 14 mm in segment 6 of the left lung
- Mediastinal lymph nodes
- a suspicious lymph node in the anterior mediastinum near the sternum, 16 mm in short axis
- Trachea and bronchi
- patent
- Pleural cavities
- no effusion
- Heart and mediastinum
- normal
- Esophagus
- patent, thin-walled
- Pulmonary trunk and arteries
- patent
- Thoracic aorta
- normal
- Chest wall
- in the upper outer quadrant of the right breast an area of pathological enhancement 33 × 27 mm; multiple pathological right axillary lymph nodes up to 17 mm in short axis
- Liver
- a hypodense metastatic lesion 45 mm in segment 8; enlarged; with features of steatosis (unenhanced density ~40 HU)
- Gallbladder
- thin-walled; with a few calculi
- Bile ducts
- not dilated
- Pancreas
- normal size; homogeneous; no focal lesions; pancreatic duct not dilated
- Spleen
- not enlarged, no focal lesions
- Adrenal glands
- not enlarged
- Kidneys and ureters
- kidneys normally located, normal size; no hydronephrosis, no calculi, no focal lesions; symmetric excretion of contrast in the urographic phase; ureters not dilated
- Urinary bladder
- smooth outline, well distended
- Reproductive organs
- a fluid space with septa and calcifications in the region of the right adnexa, 54 × 43 mm — for further workup on MRI
- Lymph nodes
- retroperitoneal, mesenteric, inguinal and pelvic nodes not enlarged
- Peritoneal cavity
- a small amount of free fluid in the pelvis; no peritoneal implants
- Bowel
- walls not thickened, no pathological enhancement
- Abdominal wall
- no discernible lesions
- Great vessels
- patent
- Bones
- disseminated lytic metastatic lesions in multiple bones within the scan range, the largest 30 mm in the sternum and 35 mm in the left iliac wing; degenerative changes of the thoracic, lumbar and sacral spine
Measurement table — RECIST 1.1
baseline · proposed target lesions| # | Target lesion (proposed) | Location | Baseline size | Measurement method |
|---|---|---|---|---|
| T1 | Right breast tumour | upper outer quadrant | 33 mm | longest diameter |
| T2 | Liver metastasis | segment 8 | 45 mm | longest diameter |
| T3 | Right lung lesion | segment 3 | 13 mm | longest diameter |
| T4 | Left lung lesion | segment 6 | 14 mm | longest diameter |
| T5 | Anterior mediastinal lymph node | parasternal | 16 mm | short axis (node ≥ 15 mm) |
| Sum of target-lesion diameters (baseline SLD) | 121 mm | reference point | ||
- pathological right axillary lymph nodes (up to 17 mm in short axis)
- disseminated lytic bone metastases (largest: sternum 30 mm, left iliac wing 35 mm)
- remaining small focal lesions in both lungs
- a small amount of free fluid in the pelvis